In mutt and neomutt the In-Reply-To email header field is not protected by cryptographic signing which allows an attacker to reuse an unencrypted but signed email message to impersonate the original sender.

In mutt and neomutt, PGP encryption does not use the --hidden-recipient mode which may leak the Bcc email header field by inferring from the recipients info.

In neomutt and mutt, the To and Cc email headers are not validated by cryptographic signing which allows an attacker that intercepts a message to change their value and include himself as a one of the recipients to compromise message confidentiality.